Phytochemical Analysis, Antimicrobial, Cytotoxic and Antioxidant Activities of Oenanthe javanica
Humayun khan
Department of Chemistry, Islamia College, Peshawar-25000, Khyber Pakhtunkhwa, Pakistan.
Muhammad Suleman khan
School of Biochemistry, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Alamgir khan
Department of Zoology, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Muhammad Jamshed
School of Chemistry, and Xi'an Key Laboratory of Sustainable Energy Materials Chemistry, Xi'an Jiaotong University, Xi'an 710049, P. R., China.
Zama Jan
School of Physics, and Xi'an Key Laboratory of Sustainable Energy & Computational Materials Science, Xi'an Jiaotong University, Xi'an-710049, P. R., China.
Uzair khan
*
Department of Chemistry, Islamia College, Peshawar-25000, Khyber Pakhtunkhwa, Pakistan, School of Biochemistry, Quaid-i-Azam University, Islamabad 45320, Pakistan and School of Chemistry, and Xi'an Key Laboratory of Sustainable Energy Materials Chemistry, Xi'an Jiaotong University, Xi'an 710049, P. R., China.
Sara Ali
Department of Chemistry, Islamia College, Peshawar-25000, Khyber Pakhtunkhwa, Pakistan and Department of Chemistry, Abdul Wali Khan University Mardan-3200 Khyber Pakhtunkhwa, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Medicinal plants are an integral part of life in many communities. They are source of vital therapeutic aid for assuaging human ailments and that is chiefly due to existence of biologically active phytochemicals. Oenanthe javanica, aquatic perennial herb, known for its medicinal values. The present research was conducted to investigate the chemical composition of essential oil extracted from Oenanthe javanica through GC-MS analysis; to evaluate the phytochemical constituents, cytotoxic capability and antioxidant activity of different extracts; and finally, to evaluate the antimicrobial potential of essential oil and different extracts of Oenanthe javanica. S-MS analysis shown that seven constituents are present in the essential oil. Phytochemical investigation has shown that Oenanthe javanica contains following components alkaloids, flavonoids, tannins, phenol, and saponins in all its extracts except n-hexane extract which lacks saponins. Among all extracts only chloroform extract is found to be cytotoxic and best values for DPPH scavenging potential was exhibited by ethanolic extract. Some of the extracts of Oenanthe javanica possess antimicrobial potential whereas essential oil was only active against tested fungal strains.
Keywords: Oenanthe javanica, essential oils extraction, phytochemical screening, cytotoxic, antimicrobial and scavenging properties