South Asian Research Journal of Natural Products

Phytochemistry and Bioactivity of Annona reticulata L. (Annonaceae): A Mini-review

Koto-Te-Nyiwa Ngbolua *

Department of Biology, Faculty of Science, University of Kinshasa, P.O.Box 190 Kinshasa XI, Democratic Republic of the Congo and Department of Environmental Sciences, University of Gbadolite, P.O.Box 111 Gbadolite, Province of Nord-Ubangi, Democratic Republic of the Congo

Clément L. Inkoto

Department of Biology, Faculty of Science, University of Kinshasa, P.O.Box 190 Kinshasa XI, Democratic Republic of the Congo

Gédéon N. Bongo

Department of Biology, Faculty of Science, University of Kinshasa, P.O.Box 190 Kinshasa XI, Democratic Republic of the Congo

Lengbiye E. Moke

Department of Biology, Faculty of Science, University of Kinshasa, P.O.Box 190 Kinshasa XI, Democratic Republic of the Congo

Lufuluabo G. Lufuluabo

Department of Chemistry, Faculty of Science, University of Kinshasa, P.O.Box Kinshasa XI, Democratic Republic of the Congo

Colette Masengo Ashande

Department of Environmental Sciences, University of Gbadolite, P.O.Box 111 Gbadolite, Province of Nord-Ubangi, Democratic Republic of the Congo

Damien S. T. Tshibangu

Department of Chemistry, Faculty of Science, University of Kinshasa, P.O.Box Kinshasa XI, Democratic Republic of the Congo

Dorothée D. Tshilanda

Department of Chemistry, Faculty of Science, University of Kinshasa, P.O.Box Kinshasa XI, Democratic Republic of the Congo

Pius T. Mpiana

Department of Chemistry, Faculty of Science, University of Kinshasa, P.O.Box Kinshasa XI, Democratic Republic of the Congo

*Author to whom correspondence should be addressed.

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Abstract

Aims: To provide knowledge on phytochemistry and bioactivity of Annona reticulata.

Study Design: Multidisciplinary advanced bibliographic surveys, utilization of ChemBioDraw software package and dissemination of the resulted knowledge.

Place and Duration of Study: Faculty of Science, University of Kinshasa and Department of Environmental Science, University of Gbadolite, the Democratic Republic of the Congo, between October 2017 and January 2018.

Methodology: A literature search was conducted to obtain information about the phytochemistry and pharmacognosy of A. reticulata from various electronic databases (PubMed, PubMed Central, Science Direct and Google scholar). The scientific name of this plant species was used as a keyword for the search, along with the terms phytochemistry and pharmacognosy. The chemical structures of the A. reticulata naturally occurring compounds were drawn using ChemBioDraw Ultra 12.0 software package.

Results: Results revealed that this plant is traditionally used as stimulant or pain reliever. This plant is reported to possess various biological properties like anti-oxidant, antimicrobial, anti-inflammatory, antihelmintic, antipyretic, antihyperglycemic, analgesic, wound healing, antisickling and cytotoxic effects. These properties are due to the presence of numerous naturally occurring phytochemicals like tannins, alkaloids, phenols, glycosides, flavonoids and steroids.

Conclusion: The present review can, therefore, help inform future scientific research towards the development of novel drugs of relevance from A. reticulata to improve human health and wellbeing. Especially drug candidates for cancer treatment or external use like wound healing medicines.

Keywords: Annona reticulate, primary health care, phyto-constituents, pharmacognosy, model system

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