Working with Bioactive Substances from Medicinal Plants in Animals
Published: 2020-07-20
Page: 78-88
Issue: 2020 - Volume 3 [Issue 2]
Idris Zubairu Sadiq *
Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
Fatima Sadiq Abubakar
National Agricultural Extension and Liaison Services, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
Hassan Aliyu Hassan
Department of Biochemistry, Faculty of Sciences, Federal University, Dutse, Jigawa State, Nigeria.
Maryam Ibrahim
Department of Biochemistry and Molecular Biology, Faculty of Life Sciences, Federal University, Dutsin-Ma, Katsina State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Background: Working with bioactive substances from the medicinal plant requires various steps from plant extract preparation to the calculation for scientific evaluation and safe medicinal plant extract administration. The paper aims to discuss procedures involve in evaluating bioactive compounds from medicinal plants.
Methodology: Review of relevant literature.
Results: We have described the preparation of plant extract, toxicological methods of evaluating bioactive substances, vehicles for biological research, evaluating analgesic, neuropharmacological and anti-inflammatory activities from medicinal plants.
Conclusion: Medicinal plants are potent stores of bioactive compounds that needed to be carefully extracted, toxicologically and preliminarily evaluated in animals for new drug development.
Keywords: Plant extract, toxicological methods, anti-inflammatory activities, evaluating analgesic activity.